Have you been diagnosed with NASH/MASH?
Participating in a clinical research study might be an option for you.
See If You Qualify
- No cost to check eligibility
- No obligation to participate
- A coordinator confirms eligibility by phone
- You can withdraw at any time
This pre-screening does not guarantee enrollment.
Overview
Researchers are studying a new medication called pegozafermin to see if it can help treat Metabolic Dysfunction-Associated Steatohepatitis (MASH), previously called Nonalcoholic Steatohepatitis (NASH), a form of fatty liver disease that can lead to liver damage over time.
The goal of the study is to learn whether pegozafermin can improve liver health and reduce liver scarring over a treatment period of about 52 weeks (one year).
Researchers will compare liver biopsy results from the beginning of the study and after one year to see whether the treatment helps improve the condition of the liver.
Join a (MASH/NASH) Fatty Liver Research Study
Your participation may help researchers learn more about potential new treatments for MASH.
About the Study
We are currently seeking patients with fatty liver for research studies focused on advancing treatments for Metabolic Dysfunction-Associated Steatohepatitis (MASH), also known as Nonalcoholic Steatohepatitis (NASH).
A Pegozafermin Study
This study is testing a new type of treatment that uses gene silencing to target MASH. This research is focused on people who have specific genetic risk factors for the disease.
By participating, you could help advance the development of new and effective treatment options for MASH/NASH.
Non-Alcoholic Steatohepatitis (NASH)
Liver Fibrosis
Benefits
Study-Related Care
Study related medication and care provided at no cost
No Insurance Needed
Health insurance is not required.
Compensation
Qualified participants may earn up to $1300 during the first year and up to $2600 throughout the duration of the study (3 years).
Who Can Join
Have a BMI of 25 or higher
Have been diagnosed with MASH (also called NASH) with liver scarring (fibrosis)
Have not had a liver transplant
*Other conditions may apply
Have other serious liver diseases besides MASH
Have had bariatric (weight-loss) surgery in the past 5 years
Have recently taken certain medications known to affect the liver
Have used investigational medications for MASH/NASH within the past 6 months
What to Expect
* Eligible participants may receive compensation for completing all required study-related activities.
Liver Biopsy
Undergo a liver biopsy so researchers can study liver health
MRI
Complete up to 3 MRI scans to help evaluate the liver
Study Visits
Attend scheduled study visits and phone check-ins with the research team
Participating Locations
Know Someone Who Might Qualify?
Share this study with a friend or family member who may benefit.