Do you take blood pressure medication?
You may be eligible for the ZENITH study
Join a study evaluating an investigational medication for blood pressure management
If you participate in the ZENITH study:
- All study-related tests and procedures are provided at no cost
- Health insurance is not required to participate
- You may be reimbursed for your time and travel
A clinical trial is a carefully designed research study involving human volunteers to investigate the safety and effectiveness of a new drug or treatment. Clinical trials are essential for evaluating the benefits and risks of medical interventions, ultimately informing healthcare decisions and regulatory approvals.
As a clinical trial or observational study participant, your responsibilities and what you will be required to do can vary depending on the study, its objectives, and the phase of the trial.
Some common activities and responsibilities you may encounter as a participant include: diagnostic tests, treatments, procedures, doctor visits, dietary changes, exercise and/or other lifestyle changes. Observational studies often involve minimal effort, such as completing questionnaires, sharing test results, maintaining a diet or exercise log.
Joining a clinical trial can provide access to cutting-edge treatments, close medical monitoring, and an opportunity to contribute to medical knowledge. Participants may experience improved health outcomes and specialized care while potentially receiving compensation for volunteering.
Clinical trials are designed with a strong emphasis on the safety of participants, and multiple safeguards are in place to minimize risks, including careful study design, oversight by institutional review boards and routine monitoring of study data by independent experts. Researchers must inform participants of the risks, benefits and/or side effects they discover.
Yes, you can drop out of a clinical trial study at any time, and you have the right to do so without facing any penalties or consequences. This is often referred to as "withdrawal of consent."
Voluntary participation is a fundamental principle of clinical research. You are not obligated to continue in a trial if you no longer wish to do so.
Determining your eligibility to participate in a clinical trial involves a thorough evaluation of specific eligibility criteria set forth by the study's researchers and sponsors. The criteria help define the patient population being studied and are designed to protect the safety of participants in the trial.
Providing accurate information about your medical history and health status is crucial for your safety and the integrity of the research. If you are not eligible for one trial, you may still be eligible for other trials in the future, so it's worth exploring your options if you are interested in participating in clinical research.
STUDY INFORMATION
Managing high blood pressure isn’t easy — and many people still struggle to keep it under control. Even with medication, many people find their blood pressure is still above target levels — this is called uncontrolled hypertension.
You may have uncontrolled hypertension if:
- Your doctor has told you your blood pressure is still high, even on treatment
- You need more than one medication to keep it under control
- Your systolic blood pressure often measures 140–180 mmHg
The ZENITH study is evaluating whether an investigational therapy may help adults better control their blood pressure.
By joining ZENITH, you may contribute to research that could potentially improve future care for people with hypertension.
Who can take part?
- Age 18+ with heart disease OR 55+ with cardiovascular risk factors (such as diabetes, kidney disease, obesity, or smoking)
- Currently taking blood pressure medication
- Have systolic blood pressure between 140–180 mmHg
***There are additional criteria you need to meet to take part.