Agitation & Alzheimer's Disease
Have you or a loved one been diagnosed with agitation associated with dementia of the Alzheimer’s type?
Benefits of Joining a Clinical Trial
Many studies include compensation for time and travel
Study related medication and care provided at no cost
Health insurance is not required.
ABOUT THE STUDY
This clinical research study is evaluating the study drug, Masupirdine (SUVN502), in adults ages 50 years or older who experience agitation associated with dementia of the Alzheimer’s type. The study will test how well Masupirdine (SUVN-502) treats agitation associated with dementia of the Alzheimer’s type. The purpose of this research study is to also learn about the safety of Masupirdine (SUVN-502) and how well you or your loved one tolerate(s) a once-aday oral dose.
What is Agitation Associated with Dementia of the Alzheimer’s Type?
Alzheimer’s disease is a progressive disease that slowly destroys nerve cells in the brain which affect memory and thought processes, resulting in a continuing decline in performing daily activities. It is characterized by non-cognitive, behavioral, or psychiatric symptoms, which are seen in 90% of individuals with dementia. Agitation is a behavioral condition that people with any type of dementia can experience. For individuals with the type of dementia caused by Alzheimer’s disease, agitation is quite common, with over half of patients experiencing it.
Common symptoms of agitation may include:
- Restlessness
- Verbal or physical aggressiveness
- Emotional distress
- Irritability
- Wandering
Individuals with agitation associated with Alzheimer’s disease may also become upset easily, resist help, appear uncooperative, and act in a stubborn or disruptive manner which can be very upsetting to families.
1 Jones E, Aigbogun MS, Pike J, Berry M, Houle CR, Husbands J. Agitation in Dementia: Real World Impact and Burden on Patients and the Healthcare System. J Alzheimers Dis. 2021;83(1):89-101. doi: 10.3233/JAD-210105. PMID: 34250934; PMCID: PMC8461728
Am I eligible?
You or a loved one may qualify if you or they:
- Are at least 50 years old.
- Have been diagnosed with Alzheimer’s disease
- Have confirmed agitation associated with Alzheimer’s disease.
- Have a caregiver or study partner willing and able to attend all study visits.
There are additional study requirements to participate. A study representative will discuss these with you.
A clinical trial is a carefully designed research study involving human volunteers to investigate the safety and effectiveness of a new drug or treatment. Clinical trials are essential for evaluating the benefits and risks of medical interventions, ultimately informing healthcare decisions and regulatory approvals.
As a clinical trial or observational study participant, your responsibilities and what you will be required to do can vary depending on the study, its objectives, and the phase of the trial.
Some common activities and responsibilities you may encounter as a participant include: diagnostic tests, treatments, procedures, doctor visits, dietary changes, exercise and/or other lifestyle changes. Observational studies often involve minimal effort, such as completing questionnaires, sharing test results, maintaining a diet or exercise log.
Joining a clinical trial can provide access to cutting-edge treatments, close medical monitoring, and an opportunity to contribute to medical knowledge. Participants may experience improved health outcomes and specialized care while potentially receiving compensation for volunteering.
Clinical trials are designed with a strong emphasis on the safety of participants, and multiple safeguards are in place to minimize risks, including careful study design, oversight by institutional review boards and routine monitoring of study data by independent experts. Researchers must inform participants of the risks, benefits and/or side effects they discover.
Yes, you can drop out of a clinical trial study at any time, and you have the right to do so without facing any penalties or consequences. This is often referred to as "withdrawal of consent."
Voluntary participation is a fundamental principle of clinical research. You are not obligated to continue in a trial if you no longer wish to do so.
Determining your eligibility to participate in a clinical trial involves a thorough evaluation of specific eligibility criteria set forth by the study's researchers and sponsors. The criteria help define the patient population being studied and are designed to protect the safety of participants in the trial.
Providing accurate information about your medical history and health status is crucial for your safety and the integrity of the research. If you are not eligible for one trial, you may still be eligible for other trials in the future, so it's worth exploring your options if you are interested in participating in clinical research.
Yes, we do! Have a friend or family member who may also want to participate in one of our studies?
For qualifying studies, we offer a $25 gift card for each friend or family member that you refer. Restrictions apply. Please ask about our referral program during your screening visit.