Major Depressive Disorder (MDD) Clinical Trial
Taking an Antidepressant That Isn't Fully Helping? Researching a Twice-Weekly Add-On Pill for Adults with Major Depression.
See If You Qualify
Thank you for your interest in our clinical research study. To see if you may qualify, please complete the form with your contact details.
- No cost to check eligibility
- No obligation to participate
- A coordinator confirms eligibility by phone
- You can withdraw at any time
This pre-screening does not guarantee enrollment.
Common Questions
What is a clinical trial?
A clinical trial is a carefully designed research study involving human volunteers to investigate the safety and effectiveness of a new drug or treatment. Clinical trials are essential for evaluating the benefits and risks of medical interventions, ultimately informing healthcare decisions and regulatory approvals.
Are clinical trials safe?
Clinical trials are designed with a strong emphasis on participant safety. Multiple safeguards are in place, including careful study design, oversight by institutional review boards, and routine monitoring of study data by independent experts. Researchers must inform participants of any risks, benefits, and side effects they discover.
What are my obligations as a participant?
Responsibilities vary by study but may include diagnostic tests, treatments, procedures, doctor visits, and lifestyle changes. Our team will walk you through everything before you commit to anything.
Can I drop out of a study?
Yes. You can withdraw at any time without any penalties or consequences. Voluntary participation is a fundamental principle of clinical research — you are never obligated to continue.
How do I know if I’m eligible?
Fill out the short form here and a member of our team will review your information and reach out to discuss the study with you. If you’re not eligible for this trial, you may still qualify for other studies we’re running.
Overview
Living with depression can feel like an uphill battle, especially when your current antidepressant medication isn’t giving you the full relief you need. If you are taking a daily antidepressant but still experiencing persistent symptoms, you are not alone. Local medical experts are currently conducting a clinical research study to evaluate an investigational oral pill. This study is looking at whether adding this twice-weekly experimental treatment to your current daily antidepressant can safely and quickly help reduce depression symptoms.
Participation Details
All study-related care and investigational medication are provided at no cost
About the Study
The main goal of this study is to test the safety and effectiveness of an experimental study medication when it is used alongside your current antidepressant.
To make sure the results are completely fair, this is a double-blind, placebo-controlled study. This means:
- Participants will be randomly assigned to receive either the active investigational pill or a matching “placebo” pill (a dummy pill with no active medicine).
- You will take 3 tablets, twice a week, for 4 weeks.
- Neither you nor the study doctors will know which pill you are taking during the study, but your health will be closely monitored the entire time.
Investigational Group
3 investigational tablets taken twice weekly alongside regular daily antidepressant monotherapy.
Benefits
If you qualify and choose to join the study, you may receive the following at no cost to you:
Investigational Medication
The experimental add-on pill (or matching placebo).
Expert Medical Care
Regular, specialized health tracking and mood evaluations by board-certified doctors and mental health experts.
Compensation
Qualified participants can receive up to $1265 to help cover the time and travel required for study appointments.
No Insurance Required
You do not need health insurance, doctor referrals, or co-pays to participate.
Who Can Join
You may qualify if you:
Are 18 to 70 years of age.
Have a diagnosis of Major Depressive Disorder (depression) and are not experiencing symptoms of psychosis.
Have been experiencing your current episode of depression for at least 8 weeks.
Have been taking one approved antidepressant medication at a stable dose for at least 8 weeks, but it is not providing enough symptom relief.
Have a Body Mass Index (BMI) between 19.0 and 40.0.
Do NOT have a history of certain psychiatric conditions, including bipolar disorder, schizophrenia, PTSD, autism spectrum disorder, a personality disorder, or severe intellectual disability, and have not been diagnosed within the past year with severe OCD, an eating disorder, panic disorder, or acute stress disorder.
Check Your BMI
Enter your details to see if you meet the BMI requirement for this study.
What to Expect
* Eligible participants may receive compensation for completing all required study-related activities.
Screening Period (Up to 2 weeks)
Initial check-ups to make sure the study is a safe and correct fit for you.
Treatment Period (4 weeks)
The timeframe where you will take the study medication twice a week.
Safety Follow-Up (1 week)
A final phone call check-in to see how you are doing.
Participating Locations
Know Someone Who Might Qualify?
Share this study with a friend or family member who may benefit.