Overview
Now Enrolling: A Fatty Liver Clinical Trial Testing a Potential New Way to Target Liver Fibrosis.
Addressing advanced liver scarring associated with Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-Associated Steatotic Liver Disease (MetALD), or Fatty Liver Disease can be challenging. If you have been diagnosed with liver fat and scarring, a local clinical research study may be a path forward.
Why Your Participation Matters:
By joining, you help researchers explore new ways to treat advanced liver disease. Qualified participants receive all study-related care and health monitoring at no cost and may be compensated for their time and travel.
About the Study
This fatty liver clinical trial has been designed to assess an investigational medication (AZD2389) which targets a protein called fibroblast activating protein (FAP); this protein is involved in the development of liver fibrosis.
We are conducting this study to measure the safety and tolerability of AZD2389, as well as how the study medication acts in the body in participants with liver fibrosis. The findings from the study will help inform the design of a larger, longer term clinical study.
Join the fatty liver clinical trial by signing up below!
Who Can Join
You may be able to participate if you:
- Are between 18 and 75 years old
- Have MASH (fat buildup in the liver that causes inflammation)
- Have advanced liver scarring (a past liver biopsy in your medical records may be used to confirm this)
- Have a BMI of 25 or higher
- Are in generally stable health
- Any medications (like for diabetes) have been stable for at least 3 months
You may not be eligible if you:
- Have active wounds or had major surgery within the past 3 months
- Have serious heart or kidney disease
- Have poorly controlled blood sugar (A1c higher than 9.5%)
- Have gained or lost more than 5% of your body weight in the past 6 months
- Drink, on average, more than 3–4 drinks a day (women) or more than 4–5 drinks a day
*Additional inclusion/exclusion criteria may apply
Not sure if you qualify?
That’s okay. A member of our recruitment team will review your medical history and medications with you to see if this fatty liver clinical trial may be right for you.
You may also qualify for other enrolling studies.
What to Expect
Here’s an overview of what to expect when you sign up for this fatty liver clinical trial:
Study Duration
Up to 32 weeks
Study Visits
10 scheduled study site visits
Compensation
Up to $1250*
* Eligible participants may receive compensation for completing all required study-related activities.