Knee Osteoarthritis Research Study

Tired of temporary fixes for your knee pain? Learn about a clinical trial.
Benefits of Joining a Clinical Trial
  • A single dose of the investigational joint injection administered at no cost.
  • Comprehensive study-related health monitoring, routine lab tests, and detailed knee imaging (X-rays and MRIs).
  • Dedicated care and ongoing monitoring by experienced study doctors and research specialists.
  • Study-provided pain relief for knee pain during the study.
  • Compensation or reimbursement for your study-related time and travel.
patient being examined for a knee osteoarthritis research study
Gender
Male and Female
Ages
40 to 80
Status
Enrolling

Overview

Join a No-Cost Knee Osteoarthritis Research Study!

Living with knee osteoarthritis can make moving around, climbing stairs, and managing daily routines increasingly difficult even if you stay active, do physical therapy, or take over-the-counter pain relievers.

Local clinical research studies are now evaluating an investigational injection for knee osteoarthritis. If you qualify, you can receive study-related medical care, comprehensive knee assessments, and the investigational study treatment at no cost to you.

See if you qualify!

See If You Qualify

About this Study

Knee osteoarthritis causes disease the protective cartilage in your joint to wear down over time, leading to chronic pain, stiffness, swelling, and limited mobility. While exercise, physical therapy, and basic pain medications help many people, others still struggle with daily pain or find that temporary remedies wear off too quickly.

This knee osteoarthritis research study is evaluating the safety and effectiveness of a single-dose investigational joint injection in adults aged 40 to 80. Researchers hope to provide a potential new, long-acting option for individuals managing knee osteoarthritis pain.

See If You Qualify

Who Can Join

knee osteoarthritis research study requirements

Not sure if you qualify? That’s okay.

A member of our recruitment team will review your health history and medicines with you to see whether you may qualify for this knee osteoarthritis research study.

You may also qualify for other studies.

See If You Qualify

Why You Should Join

What is provided if I join the knee osteoarthritis research study?

  • Investigational Care at No Cost: Receive study-related health evaluations, advanced knee imaging (X-rays and MRIs), laboratory tests, study-provided rescue pain medication, and the investigational joint injection at no cost to you.
  • Specialist Medical Monitoring: Be closely monitored by experienced local joint specialists, study doctors, and research staff throughout your study participation.
  • Advance Medical Research: Play a direct role in evaluating potential future therapies for long-term knee pain relief.
  • Compensation: Reimbursement or compensation for study-related time and travel expenses may be provided for completed clinic visits.
  • Flexible Access: No health insurance or doctor’s referral required to apply.
See If You Qualify

What to Expect

Here’s what to expect when you join our knee osteoarthritis research study?

  • Study Treatment
    • Investigational Treatment: You will receive a single, one-time study injection containing either the investigational study treatment or a placebo (sterile saltwater saline).
    • Administration: The study injection is administered directly into your knee during a single visit by a trained study doctor using ultrasound guidance to ensure precise placement.
  • Study Duration
    • Total Participation: Up to 5 years (270 weeks) total, which includes an evaluation period and long-term follow-up check-ins.
      • Screening Phase: Initial health checks, blood tests, X-rays, and an MRI of your knee to confirm eligibility.
      • Primary Evaluation Phase: Outpatient clinic visits to monitor your knee health, review pain relief, and perform routine health checks.
      • Long-Term Follow-Up Phase: Annual clinic visits and telephone check-ins to monitor your joint health long-term.
  • Health Assessments & Monitoring

During your scheduled visits, the research team will conduct routine health checks, which may include:

    • Detailed knee examinations and joint evaluations
    • Complete physical exams and vital sign checks
    • Advanced knee imaging, including weight-bearing X-rays and MRIs
    • Routine blood, urine, and safety laboratory tests
    • Tracking of your knee pain and rescue medication usage through a simple smartphone app/electronic diary.
  • Compensation

Qualified participants who enroll and complete scheduled visits may receive compensation or financial reimbursement for time and travel associated with study visits.

See If You Qualify

See if You Qualify.

To see if you qualify or to learn more, please complete the form

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Frequently Asked Questions.

What is a Clinical Trial?

A clinical trial is a research study that evaluates new medications, devices, or treatment approaches to determine if they are safe and effective. Clinical trials help doctors and researchers develop better treatments for current and future patients. All studies follow strict safety guidelines and are carefully monitored.
Each clinical study has specific requirements for participants based on factors such as age, medical history, and current health status. The eligibility criteria in each study protocol are used to identify the volunteers best qualified to participate.
No. Study-related medications, lab tests, and medical visits are provided at no cost to you. Participating in a clinical trial should never require you to pay for study-related care.
Many studies provide compensation for your time and travel. Compensation amounts vary by study and will be fully explained before you decide to enroll.
Health insurance is not required for most clinical trials. All study-related care, procedures, and doctor visits are typically provided at no cost to you.
Participation is completely voluntary. You may choose to leave a clinical trial at any time, for any reason. Your decision will not affect your regular medical care or relationship with your doctor.
Each study has specific eligibility criteria. The best way to find out if you qualify is to complete our online eligibility form or speak directly with a member of our research team.